Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.070 | GeneticVariation | BEFREE | In our genetic epidemiological studies, rs1970764 in oncogene PPP1R13L was most consistently associated with lung cancer risk. | 31483011 | 2019 |
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0.070 | GeneticVariation | BEFREE | In conclusion, our study suggests that haplotypes consisting of PPP1R13L rs1970764-CD3EAP rs961591-GLTSCR1 rs1035938 on Chr19q13.3, interaction of smoking and GLTSCR1 rs1035938-ATM rs11212592, and synergistic action of PPP1R13L rs1970764 and ATM rs11212592 may associate with lung cancer risk in the Chinese population. | 30128886 | 2018 |
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0.070 | GeneticVariation | BEFREE | The combined data suggest that the sub-region with the strongest association to lung cancer susceptibility might locate to the 23.173kb from PPP1R13L intron8 rs1970764</span> to rs62109563 3' to CD3EAP. | 27183913 | 2016 |
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0.070 | GeneticVariation | BEFREE | In conclusion, we were able to reproduce previously found associations between PPP1R13L and CD3EAP polymorphisms and lung cancer risk in an increased study group, and we found interactions between NFKB1 rs28362491-PPP1R13L rs1970764 and smoking duration and between CD3EAP rs735482 and smoking duration. | 26563375 | 2016 |
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0.070 | GeneticVariation | BEFREE | The results suggest that NFKB1 common variants and smoking duration and smoking duration-PPP1R13L rs1970764 interaction could be concerned with the lung cancer development in a Chinese population. | 25917613 | 2015 |
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0.070 | GeneticVariation | BEFREE | We addressed the effects of variants/haplotypes of PPP1R13L rs1970764 and CD3EAP rs967591 and rs735482 on susceptibility of lung cancer among nonsmoking Chinese women. | 23624123 | 2013 |
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0.070 | GeneticVariation | BEFREE | In conclusion, we found that variant alleles of PPP1R13L rs1970764 and CD3EAP rs967591 may contribute to risk factors of lung cancer, but the high-risk diplotype predefined among Caucasians was rare and the diplotype is unlikely to confer lung cancer risk in a Chinese population. | 22335888 | 2012 |